The Sun report.
The Premier League champions are starting to feel the implications of the upcoming Fifa Financial Fair Play rulings, and want to shorten their wage bill and sell some squad players this summer.
Santa Cruz has not played for the Etihad Stadium first-team in two years, and spent last season on loan at Real Betis in Spain.
However, Werder Bremen have been accredited with an interest in the Paraguayan striker and look set to make a move for him in the near future.
Meanwhile, De Jong has found a starting jersey at the club hard to come by, with the likes of Gareth Barry, James Milner and Yaya Toure preferred by Roberto Mancini in the City engine room.
The Netherlands international is wanted by Inter, who are set to launch a £7 million bid for him and offer more regular first-team football.
By Gareth McKnight