Wigan lead 17th-placed Reading by two points, but both clubs are in danger of getting sucked into the bottom three if they don’t find winning form quickly.
Reading finally broke their duck last week against Everton and are now unbeaten in four matches following successive draws against Norwich, QPR and Fulham.
Adam Le Fondre was the hero last week with his two second-half goals completing a come-from-behind 2-1 triumph over Everton.
It was the first time the 25-year-old has found the net since the opening clash of the season against Stoke.
Fellow striker Pavel Pogrebnyak has been another to impress this season and will be keen to add to his season tally of two goals.
After posting successive victories against West Ham and away at Tottenham, Roberto Martinez’s side have come crashing back down to earth with consecutive losses to West Brom and Liverpool.
Last week’s 3-0 loss to Liverpool was particularly disappointing as they were completely outclassed by the Luis Suarez-inspired Reds.
Wigan have been dealt a blow with midfielder Ben Watson set to be sidelined for a period of time after breaking his leg against Liverpool last week.
After being in and out of the side, Watson had started the past three matches and his midfield grunt will be sorely missed.
Wigan have been held scoreless just three times this year and that is down to wealth of options they have in the attacking third.
Arouna Kone has already netted four times, while Franco Di Santo has scored three goals – although the Argentinean has not found the back of the net in his past five Premier League clashes.
Even though it is still early days in the course of the season, a loss here could see either team fall back into the bottom three and heap more pressure on them heading into the busy December period.
Predictions: Wigan 2 – 1 Reading