This will be the first ever international meeting between Switzerland and Ecuador.
Switzerland have only conceded one goal in their last seven World Cup games combined.
Ottmar Hitzfeld's side were unbeaten in World Cup qualification, winning seven and drawing three of their 10 qualifiers.
Ecuador have never drawn a game at a World Cup, winning three and losing four so far.
Indeed, la Tri have won all three games in which they have kept a clean sheet in the competition, but lost all four they have conceded in.
Felipe Caicedo scored seven goals in nine games in qualification, including one run of scoring in four in a row.
La Nati have lost their last four World Cup meetings with South American sides, failing to score in their last three.
Despite finishing fourth, Ecuador had more shots than any other team in South American qualification (201).
Reinaldo Rueda's side also made the most crosses in CONMEBOL qualification (396).