Sevilla have lost just two of their last 12 games in the Europa League, though both of those defeats have come in the last three games (W6 D4).
FC Porto are the only Portuguese side to have beaten Sevilla at home in Europe, beating them 2-1 in 2011.
However, Porto have lost their last three trips to Spain in the Champions League and Europa League.
Sevilla have lost only four of their previous 24 home games in European competition (W15 D5)
Kevin Gameiro has scored six times in his last six home games for Sevilla.
Jackson Martinez has found the net three times in his previous three appearances for Porto.
Sevilla have attempted 189 crosses from open play in the competition so far, more than any other side remaining in the competition.