Valencia have won only two of their last nine games in La Liga against Sevilla (D1 L6).
Sevilla have been victorious only twice in their last six league trips to the Mestalla (L4).
Valencia haven’t lost at home in Europe since losing to Swansea in the opening Europa League game this season (W3 D2). They’ve also gone 276 minutes without conceding at home in Europe.
Sevilla have been defeated just once in their last seven away games in Europe, albeit last time out against Porto (W4 D2).
Los Che have lost only two of their last 14 knockout games contested at home, though this does include their last semi-final game at the Mestalla against Atletico in 2012 (W7 D5).
That defeat is the only time Valencia have been beaten at home by a Spanish side in Europe (W4 D1).
Los Rojiblancos have lost three of their four away games against fellow Spanish sides in Europe, the exception being the 2-0 win over Real Betis this season.
Kevin Gameiro has scored seven times in his last six games for Sevilla.
Paco Alcacer has netted seven times in 11 Europa League appearances. Only Jonatan Soriano has scored more than him in this year’s competition.
Valencia have fired 90 shots off target in the Europa League so far this season, more than any other side.