This weekend's early match features Sunderland playing host to Manchester United at the Stadium of Light.
The Black Cats are looking to get out of the bottom three, but have a daunting task playing a Manchester United team that has been improving over the last few weeks.
The Red Devils currently sit in fifth in the table, six points behind City for a top four spot after drawing with Chelsea last Sunday. United need to take three points wherever they can, especially in fixtures like this if they want to qualify for next year's Champions League.
Sunderland came back from 2-0 late last week against Liverpool to earn a point, and are looking for a similar result against United this weekend. They'll have to get past David De Gea, who has proved to be the Premier League's top goalie this season.
Here are five things to know ahead of the match...
Sunderland Can't Seem To Score Against United
Sunderland have failed to score in eight of the last 12 Barclays Premier League matches against Manchester United, and just once in the other four.
United Have Had Sunderland's Number
The Red Devils have won 21 and lost just two of their 29 Premier League games against the Black Cats.
Even At Home, The Black Cats Are No Match For The Red Devils
Sunderland have never beaten Manchester United in the league at the Stadium of Light.
Leaking goals
Sunderland are on the longest current run without a clean sheet in the Premier League at 11 games.
United Have Been Poor On The Road This Season
The Red Devils have collected just six points from their last six Premier League away games in the 2015/16 campaign so far.