The Dutchman and the Portuguese have emerged as top targets for the Old Lady, who are rumoured to be ready to sell former Red Devils star Paul Pogba to fund moves.
Despite his billing as one of Europe’s best holding midfielders, Juve are aware that with interest high they may be able to get a good enough price for him to launch their own transfer plans.
Paris Saint-Germain are said to be willing to pay in the region of £60m for the 21-year-old, while Chelsea and Arsenal have also been linked with swoops.
If the deal is done, the Turin side will look to draft in RvP and Nani, who have been long-term targets.
The former has only been at Old Trafford for two seasons, but for most of the current campaign reports have suggested that he’s grown unsettled.
Unlike van Persie, Nani has long been available, with the inconsistent winger by no means a first-team regular at the Theatre of Dreams.
As well as the United pair, Manchester City’s Edin Dzeko is an option.