England defender Jones suffered concussion during the defeat at Stoke, and is set to be sidelined for two weeks.
Meanwhile Evans has damaged his calf and is also expected to be out for a fortnight.
The injuries means Moyes finds his defensive options stretched ahead of this weekend’s clash with bottom club Fulham.
Nemanja Vidic is set to return to the first team following suspension, but Ferdinand will have to be called in from the cold.
The former England captain has been frozen out by Moyes in recent weeks, despite having returned to full training last month following a knee injury.
Ferdinand is out of contract at the end of the season, and is yet to be offered a new deal.
He is widely expected to leave Old Trafford in the summer, especially considering he has played just once since December.
“Rio is back and we will continue to use him at the right times and the right moments,” Moyes said.
“Rio has made a great contribution especially in the first half of the season. I played him in nearly all the opening eight to ten games.”
Reports had suggested the pair had fallen out after Ferdinand criticized Moyes’s decision to name his team as late as possible before games.
But Moyes has rubbished those reports, claiming Ferdinand remains a valuable member of his squad.
“He was a big part in helping me to settle in. He helped me get my feet under the table a little bit,” he added.
“He has competition for centre half, but he is very much valued and looked at as one of the senior players here.”