Red Devils boss David Moyes is set to delve into the transfer market in the coming weeks to bolster his squad after a difficult start to the season, and has made a creative midfielder a priority.
Banega has been on their radar for some time, and now the Scot is ready to mount a serious move for his services with the South American looking to move on.
The 25-year-old has been impressive for the Spaniards for a while, but is said to have grown frustrated at the club in recent times.
This has alerted Moyes, who is ready to lure the playmaker to Old Trafford in a bid to get United’s ailing season back on track.
Rated at £12.5m the silky passer is seen as a wise purchase, and a player who can make an instant impact at the club.
If he is unable to lure Banega to away from Valencia before the deadline, he may return with a summer move.
Javier Hernandez could also be used as part of a potential deal, with Los Che known to be interested in the out-of-favour Mexican.