Speculation over the weekend suggested that the Meseysiders are close to reaching an agreement for the Croatian centre-back worth between £16m-£20m.
With Lovren have already said that his “head is already at Liverpool” a few weeks ago, it looks likely that he will become the third Saints player, after Adam Lallana and Rickie Lambert, to switch to Anfield this summer.
The South Coast club are now thought to be planning for like without the classy enforcer, and Caulker has emerged as a target.
The England international has been on Liverpool’s radar after being relegated with Cardiff last term.
Bids of £8m are said to be enough to trigger a release clause in his Bluebirds deal, and Southampton are confident of beating Crystal Palace and QPR to his signature, despite talk of the player undergoing a medical with the latter.
Caulker may well be tempted by life at St Mary’s Stadium, with Ronald Koeman’s side unlikely to embroiled in the sort of relegation fights he could face at Loftus Road or Selhurst Park.