The 33-year-old midfielder is set to leave the San Siro in the coming weeks when his contract expires, and it is understood that Spurs are showing an interest.
Cambiasso – an Argentina international – possesses a wealth of experience, and is thought to be a top target for Lilywhites chief Mauricio Pochettino.
The former Southampton manager is kicking plans into gear to drag Tottenham back into top four contention after a sixth placed finish last term, with adding more know-how to his engine room a priority.
The veteran playmaker has the experience he craves, and is available for nothing with Inter having failed to reach an agreement to keep him in Milan.
Although keen, Pochettino will have to offload one of his current crop on midfielders in order to make room for the South American.
Etienne Capoue is one name being linked with a move away from White Hart Lane after 12 disappointing months as a Spurs player.