West Ham's annual visit to Old Trafford is not normally a welcomed away day for the Hammers as the claret and blues have failed to record a victory in Salford since May 2007.
Carlos Tevez's strike kept West Ham a Premier League team then, but now Slaven Bilic faces the unenviable task of having to end that horrible record this weekend.
The Irons' season can only be deemed a disappointment after they defied the odds last term to finish seventh, when many tipped them for relegation in their final season at Upton Park.
This campaign has witnessed the historic move to the London Stadium, but the team's on-field failings have made the move an unwelcomed one. A victory at Old Trafford may finally change West Ham's fortunes and spearhead the east Londoners' rise up the Premier League table and away from the danger zone, though.
Bilic's boys are capable of overcoming United and here are THREE reasons why the Hammers can emulate that special day in 2007 once again.
Man United's dreadful home form
For the past two decades, Old Trafford was a fortress for Man United and the catalyst behind their success in achieving domestic honours.
Nonetheless, this season United's apparent fortress looks more fragile than a sandcastle, as far too regularly teams are going to Salford and walking away with at least a point.
The Hammers were known for causing upsets last season and this weekend's visit to the 'Theatre of Dreams' could provide yet another shock, with the pressure firmly on Man United to achieve three points for only the second time since August.
West Ham almost caused an upset against Spurs
Only a poor final few minutes against Tottenham prevented a memorable win for Bilic's West Ham last weekend.
Football is a game of ninety minutes, and if the Irons can keep their focus for the entirety of the game, a shock could truly be on the cards.
A dominant midfield display by the Irons almost secured a historic win against their London rivals, and if they can produce a similar showing in Manchester, then West Ham are increasingly likely to end a nine-year wait for a victory at Old Trafford.
The Hammers' aerial threat
The last gameweek perfectly summed up the above statement. Against Tottenham, Michail Antonio recorded his 11th headed Premier League goal in 2016, equalling the record for most headed goals in a calendar year.
On the contrary, Man United conceded a last minute equaliser to Arsenal when Olivier Giroud rescued a point for the Gunners at Old Trafford... with a header. Since the loss of Eric Bailly, Man United's set piece defending can only be classified as shambolic.
With Payet's form mesmeric, Antonio will be hopeful of adding to his headed goals tally, while other physically imposing West Ham players will also have to be dealt with.