McManaman initially picked up the injury during the FA Cup victory over Everton at Goodison Park and was also forced off during the victory against Newcastle last time out.
Boss Roberto Martinez has now revealed he is a big doubt for the crucial clash against the Canaries this weekend and he will be monitored over the next couple of days.
“Callum’s been carrying an injury to his ankle, which caused him to be substituted against both Newcastle and Everton,” Martinez told reporters.
“Our major concern now is making sure he’s fully fit and able to take to the field against Norwich.
“He hasn’t trained with the rest of the team yet, and the next 48 hours will be crucial.”
Latics are three points adrift of safety going into the game and Martinez can ill afford any more injury problems at a crucial stage of the season.
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