Arsenal captain Cesc Fabregas has failed to recover from a hamstring injury and will miss Wednesday's Champions League clash with Shakhtar Donetsk.
The influential Spanish midfielder will not travel with the rest of the squad to Ukraine after picking up the problem during Saturday's 1-0 victory against West Ham United.
Gunners boss Arsene Wenger confirmed:"He has a good chance to play on Sunday (against Newcastle United) but Wednesday night is too risky.
"He has no real strain, just a bit of pain. I don't know what it's down to but we cannot take a gamble as he has had injuries before. There's still a bit of reluctance to push it 100 per cent.
"Alex Song has a problem with his calf which we will assess today and he may not to travel.
"Arshavin has a problem and we might leave him at home and Denilson has a groin problem. The one that is definitely out is Fabregas, the three others will be assessed later."