Everton stunned Chelsea in a fourth round FA Cup replay, while Stoke and Birmingham cruised to easy fifth round victories on Saturday.
Chelsea – the reigning Premier League champions – who sit outside the top four in the title race, were bundled out of the cup on penalties, with Everton winning 4-3 after Leighton Baines’ brilliant 119th minute equaliser forced the match to spot kicks.
Leon Osman went close twice in the early stages while Phil Jagielka was pleased to see his defensive header hit the post and bounce away.
Chelsea could have had a penalty just before half-time but instead of a spot-kick, Ramires was given a yellow card for diving.
In the second half the hosts exerted their dominance and could have scored through Frank Lampard, twice, and Branislav Ivanovic, but Everton did have the ball in the back of the net in the last minute of normal time, only for Marouane Fellaini’s effort to be ruled offside.
Chelsea did eventually score, with Lampard capitalising on good work from Nicolas Anelka to smash home a 103th minute goal.
But Everton would not lie down and equalised thanks to Baines, who in the last minute of injury time, blasted a free-kick into the top right-hand corner which left Chelsea goalkeeper Petr Cech with no chance.
It took the game to penalties and Baines quickly went from hero to villain, hitting a weak penalty which was saved by Cech, just after Lampard had kick-started the shoot-out with a goal.
Didier Drogba and Jagielka both scored before Anelka had his effort saved by Tim Howard, and Arteta levelled the score at 2-2.
Michael Essien and John Heitinga both scored, but Ashley Cole could not handle the pressure, blazing over with his side’s last penalty.
It left Everton skipper Phil Neville to step up and score the winning penalty, delighting the away fans and sending the Toffees through to a fifth round tie against Reading at Goodison Park on March 1.
In other matches, Birmingham City had little trouble in accounting for League One Sheffield Wednesday, winning 3-0 at St Andrew’s.
Chilean Jean Beausejour gave Birmingham a sixth minute lead and Obafemi Martins’ strike 12 minutes later virtually assured the hosts’ progression.
David Murphy grabbed the third early in the second half to book a spot in the sixth round for Alex McLeish’s men.
Stoke City also thumped a League One outfit, with table-toppers Brighton on the end of a 3-0 loss at the Brittania Stadium.
All three goals came in the first half with John Carew, Jon Walters and Ryan Shawcross netting for Tony Pulis’ side.
Manchester United face non-league Crawley Town in the 1715 (GMT) kick-off.