Fulham's game against Portsmouth on Saturday is the first Premier League game of the weekend to fall foul of the big freeze, while Liverpool versus Tottenham on Sunday is expected to follow suit.
Craven Cottage was scheduled to host the visit of Pompey at 3pm on Saturday but the game has been postponed due to a combination of a frozen pitch and the hazardous nature of the approaches to the stadium.
"The safety of supporters is of paramount importance to the club and following an inspection of the areas surrounding Craven Cottage on Friday morning, it was deemed unsafe for fans to travel," read a club statement.
Meanwhile, Liverpool have requested a postponement of their home clash with Tottenham at Anfield 24 hours later on the same grounds.
A club statement read:"Liverpool Football Club have submitted an official request to the Premier League that Sunday's Barclays Premier League clash against Tottenham be called off for safety reasons.
"Discussions with the Premier League are currently taking place and more news will be announced as soon as a final decision is made."
The Football League and Scottish programmes have already been decimated by the prolonged icy weather which is blighting the British Isles.