The Craven Cottage attacker was dismissed controversially on 29 minutes for pushing Gervasio Nunez, which set the tone for the remainder of the match.
David Biton scored the decisive goal for the home side on 60 minutes, and Fulham now have work to do in Group K to ensure qualification to the next round.
Cottagers manager Martin Jol was understandable disappointed after the match, and felt the red card changed the game.
“You could say it was a frustrating evening,” he told Sky Sports after the defeat.
“Before the sending off I think we were in control. The pace was good, possession play was good and I was very satisfied. Then we got a straight red card and that makes it difficult for any team.
“After that they had more confidence, of course, because they played with 11 players and it was an awful night for us. Even after that we should have had a couple of decisions. You can’t say anything about the referee, bad or good,” he concluded.
Fulham will look to put the loss to the back of their minds as they host Everton on Sunday, and as they have only won one game in the league this season will hope for three points.
By Gareth McKnight