The temperamental midfielder was dismissed for elbowing Carlos Tevez, before trying to knee Sergio Aguero and head-butt Vincent Kompany.
As it was not Barton’s first dismissal of the campaign, the red card carries a mandatory four-match ban, and the same sanctions were imposed for the other two acts of violent conduct.
In addition Barton has been fined £75,000, with the FA making an example out of the midfielder.
“There are rules of conduct that should be adhered to, and such behaviour tarnishes the image of football in this country, particularly as this match was the pinnacle of the domestic season and watched by millions around the globe,” a statement from the regulatory commission reads.
It is not yet known if QPR will appeal the sanctions, but Barton looks set to miss a large chunk of the start of next season.
By Gareth McKnight