Tottenham go in search of their first win at Old Trafford since 1989 on Saturday evening on the back of two consecutive Premier League victories.
This fixture has been famed for controversial decisions in recent seasons, with Tottenham rightly feeling they are due a bit of luck at the Theatre of Dreams.
Sir Alex Ferguson’s men have yet to hit their best form this season, but currently sit 2nd with 12 points out of a possible 15.
Last weekends result at Liverpool was a classic example of picking up a result despite playing poorly.
Antonio Valencia is United’s major injury concern after the Ecuador wide-man suffered an ankle injury at Liverpool last week and Ferguson rates him as “doubtful”.
The Scot also has a defensive headache to deal with after club captain Nemanja Vidic underwent knee surgery on Tuesday to rule him out for eight weeks.
Phil Jones (knee) and Chris Smalling (broken metatarsal) are still on the sidelines, meaning Rio Ferdinand and Jonny Evans are United’s only fit central defenders.
Brad Friedel will return in goal for Tottenham’s trip to Old Trafford after Carlo Cudicini took over for the midweek Capital One Cup triumph over Carlisle. Hugo Lloris is likely to return to the bench.
Emmanuel Adebayor (hamstring), Scott Parker (Achilles), Jake Livermore (groin), Benoit Assou-Ekotto and Younes Kaboul (both knee) are all missing for Andre Villas-Boas.
Prediction: Manchester United 2-0 Tottenham