Manchester United will play Arsenal in the quarter-finals of the FA Cup providing the Gunners can beat Leyton Orient.
Manchester City or Aston Villa will host the winners of Everton-Reading, while Stoke will be at home to either West Ham or Burnley.
In an all-Premier League tie, Birmingham will face Fulham or Bolton.
The quarter-final ties will be played on March 12-13.
Premier League leaders Manchester United last met Arsenal in the FA Cup in 2008 when the Red Devils were 4-0 winners, while Arsene Wenger’s side triumphed over United in the 2005 final on penalties.
The draw: Stoke v West Ham or Burnley; Manchester City or Aston Villa v Everton or Reading; Birmingham v Bolton; Manchester United v Leyton Orient or Arsenal.