Manchester United have had a difficult season so far and now face a challenge to qualify for the Champions League next season, but they may have just had another setback to their season as Fabrizio Romano delivers some bad news from the World Cup qualifiers.

What's the word?

The popular transfer insider revealed that Man United striker Edinson Cavani has picked up an injury during international duty for Uruguay.

Romano tweeted: "Bad news for Manchester United as Edinson Cavani leaves the pitch with an injury during Uruguay game."

Worrying for United

Despite lacking in game time for Manchester United this season due to the arrival of Cristiano Ronaldo, Ralf Rangnick will surely be worried that the attacker won't be able to provide depth as an option for the team in the front line ahead of their desperate chase for a top four spot this season.

The 35-year-old has fallen out of favour at Old Trafford, but has also been on the receiving end of numerous injury issues this term which has led to reduced game time, but there is no doubt that when he has been available for selection that he has been a reliable attacking threat in the team.

Cavani has scored 19 goals and delivered seven assists for his Man United team-mates in 56 appearances over the last two campaigns, with a goal involvement every 113 minutes. The majority of his contributions at the club led them to a second place finish last season under Ole Gunnar Solksjaer, scoring ten Premier League goals.

With that being said, in the moments where Rangnick's side may be in need of a late goal, having Cavani as an option off the bench to come on and deliver would have been advantageous to the Man United boss over the remaining Premier League fixtures.

They cannot afford to drop points in their pursuit of top four with Arsenal and Spurs bringing tight competition to the Red Devils.

According to Manchester Evening News, the extent of the injury is currently unknown, however it seems unlikely Cavani will feature against Leicester at Old Trafford this weekend.

In other news: Rangnick must wield the axe on "embarrassing" £180k-p/w MUFC dud this summer - opinion