This fixture should have been one of the biggest of the season, but the woeful campaigns for both sides mean it has more of a midtable clash vibe about it.
Louis van Gaal’s job continues to be under severe pressure, whilst Chelsea’s interim manager Guus Hiddink will be hoping for his first win of his second spell in charge of the club.
Diego Costa will miss out through suspension, whilst Wayne Rooney is expected to return to the starting XI for a match that could well be the Dutchman’s last in charge of the club.
A defeat for either side could have pretty disastrous consequences so we are expecting a tense affair and possible some pretty heated exchanges in a huge match.
Chelsea are also thought to be without the creativity of Cesc Fabregas, who has suffered a virus, whilst United continue to be without Luke Shaw.
Here are SEVEN stats to whet the taste buds..
Chelsea have inflicted more defeats over Manchester United in the Premier League than any other club (16).
Many of those defeats were at the hands of Jose Mourinho, but apparently he has left the club now..
Wayne Rooney has scored six goals in his last 11 Premier League starts against Chelsea.
He has only scored as many PL goals as Steven Gerrard in 2015, but Rooney will be glad to come up against one of his favourite clubs.
Man Utd have lost four competitive matches in a row within a single season for the first time since October-November 1961.
LvG continues to make stunning history at Old Trafford.
Hiddink has a superb record against Louis van Gaal and will be hoping to add to that this evening.
Guus Hiddink has won his last three competitive meetings with Louis van Gaal; all with PSV against AZ Alkmaar in the Netherlands in 2005-06.
There have been five red cards in the last six Premier League meetings between these two sides; three to Chelsea, two to Man Utd.
The fate of Van Gaal could be decided on a red card if history is anything to go by..
In the absence of Diego Costa, who scored two on Boxing Day, finding the net against United’s rock-hard defence will be harder than ever. The Blues have to contest with this stunning stat if they are to taste victory:
The Red Devils have kept six clean sheets and conceded just three goals in their eight Premier League home games in 2015-16.
The last three fixtures between these two sides at Old Trafford in the Premier League have produced just three goals in total.
Unfortunately for all the viewers, there is yet another statistic to suggest that this could be a pretty tedious affair at Old Trafford.