The young defender enjoyed a promising campaign last season, making 12 appearances for the Reds and his strength and pace as well as his versatility has made him an England U-21 regular.
However, the arrivals of Mamadou Sakho and Kolo Toure in the summer has made the road to a first XI spot at Anfield agonisingly long, and Wisdom is currently struggling to get any action.
Now, Brendan Rodgers is happy to let him go out on loan to gain experience.
Newly appointed Derby manager Steve McClaren, on the other hand, is keen to strengthen his defence. Having conceded 20 goals in 12 outings, the Rams back line is leaking badly, and arguably cancels out the fact that their attack is the highest scoring in the league.
Derby came away from this weekend with a big win at Watford, and McClaren may see the addition of Wisdom as the secret ingredient that could spur the Rams on to a place in the play-offs.