The powerful Spaniard has been heavily linked with a Premier League switch for some time, after growing frustrated by a lack of progress at the Ramon Sanchez Pizjuan.
Manchester United, Arsenal and West Ham have all been mooted as potential destinations, but now City have joined the queue and made an official enquiry ahead of a possible move.
New Citizens coach Manuel Pellegrini has already swooped to take Jesus Navas from Sevilla to the Etihad Stadium and is keen to reunite the winger with Negredo.
With Carlos Tevez having been sold to Juventus, the Chilean has just two recognised forwards in his ranks – Edin Dzeko and Sergio Aguero – a problem he is keen to address.
Sevilla are in no hurry to sell their star man, but are aware that he is looking to move on in search of Champions League football.
Pellegrini can offer him this, which may well tempt Negredo.
The 27-year-old managed 25 goals in 36 La Liga appearances during 2012/13, making him the highest scoring Spaniard in the division.
Although individually the ex-Real Madrid man was impressive, Sevilla failed to make a real impact, finishing in a mid-table position.
Manchester City fans, would you like to see Alvaro Negredo in your team?
Join the debate below!
[cat_link cat=”manchester-city” type=”grid”]