The 20-year-old has endured a lengthy period on the sidelines following back and ankle injuries.
Sir Alex Ferguson confirmed that he is planning to use Jones now he is sure the England international is back to full fitness.
“It’s a big day for Phil. He’s been out all season but has done enough training to make sure his fitness is okay,” Ferguson told SkySports.
“They’ve all been different types of injuries and because he is young, he’s still to develop physically. He’s only 20 years of age so there’s plenty of time for him.”
The Scot also confirmed that Nick Powell will feature and that he has no worries regarding his lack of experience.
“Most of them will have experience of big games and big crowds,
“Obviously for Nick Powell it’s completely different – he’s played in front of 76,000 as a substitute but this will be his first European away game.
“It will be a big day for him but he has the temperament, which is important.”
Fergie saw his team eliminated from the competition in Turkey 19 years ago during an intimidating game at the Ali Sami Yen Stadium, but he does not fear a repeat result this time out.
“We’ve been here a few times since and we’re getting used to the Turkish fanaticism and enthusiasm. It’s no issue for us,” he added.