The Red Devils snapped up teenager Anthony Martial from Monaco over the summer, and now it seems their youth-orientated transfer approach is continuing.
Reports claim that Collins is on their radar, while Newcastle and a host of Premier League clubs are interested in the 18-year-old.
The youngster has only made a handful of appearances for the League Two side, but the Red Devils are understood to have been paying close attention to his progress since signing Regan Poole from The Exiles over the summer.
Collins, who is most at home as a centre-forward, was born in Newport and has represented Wales at U-19 level.
Ex-England defender Terry Butcher is in charge of the fourth tier side and gave Collins his first-team break at the club.