Liverpool and Tottenham's Anfield clash represents the biggest fixture in the Premier League this weekend. The two sides are separated just by two points in the table and will be desperate to finish on the right side of the top four line when the season comes to a close - making this Sunday's 4.30pm kickoff something of a six-pointer.

So, who is likeliest to come out on top, which manager faces the biggest injury problems and can history tell us anything about how this one will pan out? Here's everything you need to know ahead of Sunday's game...

What History Tells Us

There's no doubt about it, Liverpool have enjoyed the upper hand in this fixture throughout the Premier League era. In fact, Tottenham's victory in the reverse fixture back in October was their first victory over the Reds in any competition since 2013.

And that gap is even more considerable at Anfield, where Tottenham have only ever taken the three points on two occasions in the Premier League, starkly juxtaposing Liverpool's 64% win rate for Spurs' trips to Merseyside. The two teams have been much closer in terms of clean sheets though and with Harry Kane chasing down his 100th Premier League goal, another this weekend will give Tottenham a huge chance of an Anfield win.

Premier League Form

There's little to choose between both sides in terms of recent Premier League form, although Tottenham will feel they've been the more consistent side over the last five games - claiming one point less but avoiding defeat, unlike Liverpool who unexpectedly lost to Swansea City, and keeping two more clean sheets than Sunday's opponents.

However, the Reds' four wins from five includes that huge victory over Manchester City and that will give Jurgen Klopp's side real confidence of demolishing another Big Six rival in a high-intensity game in front of a packed Anfield. The good news for both teams, and the neutrals, meanwhile, is that top scorers Mohamed Salah and Kane are in predictably strong scoring form at the moment.

Referee Influence - Jonathan Moss

Jonathan Moss may well be one of the Premier League's strictest referees, ranking in the top seven from the 19 officials to work in the top flight this season for fouls per tackle, fouls per game, penalties per game and yellow cards per game, and Tottenham must be particularly wary of that this weekend.

They've averaged the third-most fouls per match of any Premier League side away from home this season, while Liverpool average the sixth-fewest at Anfield, so they appear the likeliest to suffer from Moss' disciplinarian style.

That being said, only Martin Atkinson has a lower percentage of home wins this season and after officiating 18 games, that can't simply be a coincidence on Moss' part. Perhaps the 47-year-old has an inadvertent reluctance to agree with the home support.

Team News

Nathaniel Clyne remains the only long-term absentee for Liverpool, although it remains to be seen if Adam Lallana and Ragnar Klavan will be fit enough to be available for selection by the time Sunday comes around.

At this point in the season, Liverpool's front-line picks itself and is essentially untouchable, while the defence now has some much-needed familiarity to it as well. While there have been concerns over his match fitness, we're expecting Virgil van Dijk to come back into the side at the expense of Dejan Lovren.

In midfield, meanwhile, Jordan Henderson looks set to keep his place at the base of the engine room, and this game seems perfect for Alex-Oxlade-Chamberlain who was so formidable against Manchester City in the 4-3 win.

Most Reds fans would like to see Emre Can get the nod after scoring against Huddersfield in midweek, but Klopp has often shown a preference for 45-cap Dutchman Georginio Wijnaldum in the left central midfield slot - especially against high-quality opponents.

Tottenham are boasting something near a clean bill of health heading into Sunday's game, although Mauricio Pochettino will likely view next week's FA Cup replay with Newport as the preferred occasion to bring the likes of Toby Alderweireld and Danny Rose back into the fold. There's also a question of whether Deadline Day signing Lucas Moura is ready to be involved in a matchday squad after only arriving from PSG earlier this week.

Accordingly, we're predicting a largely unchanged starting XI from the one that carved open Manchester United on Wednesday night with a ferocious start at Wembley. The only difference is 6 foot 2 anchorman Victor Wanyama coming into the midfield at the expense of Eric Dier - the Kenyan seems the better option on paper and now appears to have put his injury problems behind him.

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