Tottenham Hotspur are within touching distance of a chance to land their first piece of silverware in over 12 years, but standing in their way are Championship promotion hopefuls Brentford in tonight's Carabao Cup semi-final clash.

Jose Mourinho labelled this match the biggest since he replaced Mauricio Pochettino in November 2019, so we can expect Spurs to come out with a strong lineup at the Tottenham Hotspur Stadium.

Spurs were handed a rest between their draw with Wolves and their win over Leeds United last time out due to the postponed fixture against Fulham, so that should further hint that we shouldn't expect too many alterations to the starting XI.

Here's what we are predicting this evening...

Mourinho will be forced into a couple of changes, at least.

Right-back Matt Doherty is suspended after receiving a late red card against the Whites, whilst Sergio Reguilon, Erik Lamela, Gareth Bale and Giovani Lo Celso are all expected to be absent.

That means Serge Aurier is a shoo-in to return having not featured in Spurs' last two outings. He's one of two changes to the backline as Davinson Sanchez gets the nod over the rested Toby Alderweireld.

Both Ben Davies and Eric Dier keep their places.

In midfield, there could also be some fresh legs added in the form of Moussa Sissoko. The £18m-rated Frenchman could take the place of Harry Winks, who has now started three successive matches.

Pierre-Emile Hojbjerg remains, though Mourinho has a massive call to make on Dele Alli.

The out-of-favour attacking midfielder played 66 minutes against Stoke City in the last round and could reprise that role here over Tanguy Ndombele, who has played more than 70 minutes in back-to-back matches.

We may also see one final change in the attack with Lucas Moura getting an opportunity to impress in this competition once again, which means Steven Bergwijn is axed.

The £36m-rated Brazilian, dubbed a "nightmare" by Dier hasn't started in the top-flight since October as in need of minutes, whilst the Dutch winger has concerns over his fitness.

Given the importance of the match, both Heung-min Son and Harry Kane should start.

AND in other news, Mourinho will be regretting his decision over £12m gem way better than Doherty...