Tottenham Hotspur will be hoping to advance to the quarter-finals of the Champions League when they host Juventus in the second leg of their last 16 tie at Wembley on Wednesday night.

Spurs looked to have a tough task to progress when they found themselves 2-0 after just nine minutes in the first leg in Turin last month, but Harry Kane scored ten minutes before the break to bring them back into the game.

A missed penalty by Gonzalo Higuain on the stroke of half-time proved to be the turning point, with Christian Eriksen securing a 2-2 draw for his side against the Serie A giants.

The north London outfit know that any win or a goalless or 1-1 draw will be enough to take them through to the last eight, and they will be confident of achieving that given they are unbeaten in their last 17 fixtures in all competitions, with their last defeat coming against Manchester City in December.

Mauricio Pochettino's men have also only lost at Wembley twice all season – with their previous reverse at the stadium coming in October – and he will know the importance of this match for the club both now and in the future in terms of revenue, keeping their stars and future player recruitment.

Pochettino has made minor changes to his XI in recent weeks between games in Europe, the FA Cup and the Premier League, and he could be tempted to make some more against the Italian team to ensure they get the result that they want.

Here is how Tottenham must line up against Juventus on Wednesday, ahead of Hugo Lloris in goal…

Defence

With Toby Alderweireld set to miss out against Juventus as he continues to get back to fitness following his injury, Davinson Sanchez and Jan Vertonghen pick themselves at the heart of the back four right now.

Ben Davies also looks to be ahead of Danny Rose in the pecking order at left-back, but things are less clear on the opposite flank.

Serge Aurier started at right-back against Juventus in the first leg and against Huddersfield Town on Saturday, but as he is suspended for the second he will be replaced by Kieran Trippier, and that could prove to be a blessing given the Ivory Coast international clumsily gave away the penalty that Gonzalo Higuain missed last month.

Midfield

Eric Dier and Mousa Dembele have played alongside each other in the middle of the park for the majority of the campaign with Victor Wanyama absent with a knee injury, and the Kenya international has struggled to break into the XI on his return.

While he did start the 1-0 win against Crystal Palace, he once again found himself on the substitutes' bench against Huddersfield Town on Saturday and he should find himself there again given the good form that both Dier and Dembele seem to be in right now.

Attack

Pochettino once again has some big decisions to make for the three attacking midfield positions against Juve, with Dele Alli, Christian Eriksen, Son Heung-Min, Erik Lamela and Lucas Moura all fighting for a spot in the XI in recent weeks.

Lamela got the nod against the Italian giants in the first leg but he was only a substitute against Huddersfield at Wembley – alongside Lucas – and the Argentine must start the home leg too with the Brazilian and Alli settling for places on the bench again against Juve, with Eriksen and the in-form Son – who has scored four goals in Spurs' last two games – both deserving to start.

Harry Kane will once again lead the line up top, as he looks to fire Tottenham to the quarter-finals of the competition for the first time since they faced Real Madrid in 2011.

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