Harry Kane left Tottenham Hotspur’s clash with Southampton on crutches, per The London Evening Standard’s Dan Kilpatrick.

The England captain sustained what appeared to be a hamstring injury during the encounter at St Mary’s.

After receiving a chipped ball over the top, Kane volleyed it into the back of the net, only to be flagged offside and injure himself in the process.

He was swiftly substituted for Erik Lamela and Spurs appeared somewhat toothless for the rest of the game as they fell to a disappointing 1-0 defeat.

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And several fans have taken to Twitter to react to the news that he was not able to leave St Mary’s unaided.

Of course, Kane’s likely absence from the upcoming games against Middlesbrough and Liverpool, one in the FA Cup and one in the Premier League, means that there is a void to be filled up front.

And fans have speculated as to who could replace him in Jose Mourinho’s starting XI, with two leading contenders: Troy Parrott and Son Heung-Min.

Spurs’ defeat to Southampton leaves them sixth in the Premier League, six points behind fourth-placed Chelsea and one behind fifth-placed Manchester United.

Meanwhile, Spurs fans have reacted to a link with a striker.