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Tottenham Hotspur can seal progress to their first Champions League semi-final in a generation on Wednesday, as they take on Manchester City at the Etihad Stadium.

Mauricio Pochettino's side won the first leg of the quarter-final 1-0 at the Tottenham Hotspur Stadium, meaning any kind of draw or win, or even a 2-1 loss, would see them safely through to a last-four encounter with Ajax, who conquered Juventus in Turin on Tuesday.

They will be without Harry Kane, however, after the England captain sustained ligament damage during the first leg.

Dele Alli, meanwhile, is likely to wear a protective cast after sustaining a broken hand in the first leg.

With Kane injured, it is likely that Spurs will favour a counter-attacking gameplan.

It worked to great effect against Borussia Dortmund in Germany as Spurs picked up an excellent 1-0 win at Signal Iduna Park, and could do so again, with Spurs looking to break with pace and aggression.

With that in mind, Football FanCast has put together a predicted XI for the encounter...

The big talking point here is clearly Victor Wanyama's selection.

The Kenya international returned to form against Huddersfield Town at the weekend, scoring in the 4-0 thumping of the Terriers.

Lucas Moura playing through the middle, with the support of Christian Eriksen and Heung-Min Son, allows Spurs the opportunity to counter with lightning speed, and it would also be mightily harsh to drop the Brazilian after his hat-trick against Huddersfield!