The Spaniard featured 256 times whilst on the south coast, and by the end of his tenure had struck up a finely balanced partnership with James Ward-Prowse.
His absence will be felt heavily, but one man from their past who would have filled his vacancy with ease is Victor Wanyama.
It is clear that Mauricio Pochettino thought highly of him, to bring him along as he too had made that same switch.
The Kenyan midfielder featured 97 times for both Spurs and the Saints, but the season prior to his transfer was when he truly shone.
He recorded a 7.00 average SofaScore rating, whilst managing 2.3 interceptions and 3.1 tackles per game, a marked improvement from Romeu’s final season. He was labelled a “destroyer” who was “so powerful” by journalist Jack Rathborn that season.
With a huge Romeu-shaped hole in their midfield now, adding a prime Wanyama back into the fold would be perfect for Ralph Hasenhuttl.
He was strong, a good passer and tackler, and had an incredible engine; ingredients perfect for the Austrian to work with.
If he could return, fans would quickly forget about their absent Spanish stalwart in favour of the return of the true midfield powerhouse.