Jose Mourinho will want to see a reaction from his Tottenham Hotspur side this evening after they were demolished by recently goal-shy Liverpool in midweek, though his team selection will be rather interesting.

He is going to have to make changes with leading talisman Harry Kane absent through injury, and if his half-time defensive inquest is to be believed, it would be a surprise to not see alterations to the XI after they leaked three goals to the defending champions, who had been on a run of four straight games without scoring.

But who will feature against relegation candidates Brighton and Hove Albion at The Amex this evening?

Here's the lineup we're predicting for this Premier League encounter...

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There could be as many as four changes with Mourinho reverting to a back four, in which there are two players axed as a result of Thursday night's embarrassment.

Eric Dier and Matt Doherty are surely in the firing line after a catalogue of errors against the Reds, so we could see a long-awaited return for Toby Alderweireld, who has been snubbed in four of their last five league outings, to partner Joe Rodon.

Whilst Ben Davies moves back to the left flank with Serge Aurier getting a chance at redemption having been hauled off at half-time.

In midfield, we're likely to see Moussa Sissoko return to the fray. He has started 12 of their 18 league games, and with the change to a back-four, there's a place for him alongside Pierre-Emile Hojbjerg with Tanguy Ndombele being pushed further forward.

With no Kane, it gives Mourinho a major dilemma. It's rather damning that he didn't turn to Carlos Vinicius when the England colossus came off injured, so he may not be given an opportunity here either.

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Heung-min Son is best suited to a left-wing role, so we may see Gareth Bale gifted a rare chance to lead the line. He came on to score the winner in this exact fixture back in November and played his first full 90 minutes six days ago. He should be raring to go.

Another player facing Mourinho's wrath is Steven Bergwijn, so Lucas Moura, who has been dubbed a "nightmare" to train against by Dier, is in line to start on the right.

The £25m arrival from PSG in 2018 hasn't started much this term (four league games), but his energy will be needed in the attack without Kane after Bergwijn played 81 minutes only three nights ago.

AND in other news, Ardiles & Villa 2.0: Levy could form another deadly Spurs duo signing £25.2m-rated star...