Tottenham Hotspur return to Premier League action this afternoon and Nuno Santo is dealing with several selection concerns.

His team head to Crystal Palace, who are led by former Arsenal captain Patrick Vieira, for the early kickoff, and they do so without several key players who have helped contribute to their perfect league start.

Indeed, Spurs are yet to lose a match or concede a single goal since the start of the 2021/22 Premier League campaign.

What sort of side could the Portuguese head coach opt for, considering the nightmare situation on his hands? Football FanCast takes a look ahead of kickoff...

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There are serious doubts over the fitness of Steven Bergwijn and Heung-min Son, who both picked up injuries during the international break. Both have started all three league games under Nuno, so it's certainly a cause for concern.

Meanwhile, the Lilywhites' South American trio of Giovani Lo Celso, Davinson Sanchez and Cristian Romero are definitely unavailable as they are still in Croatia and will not return until next week.

That means there will be at least one enforced change to the backline and we think it could be a simple one. Joe Rodon is the only senior centre-back available as an alternative to the aforementioned two, so he should come straight in for Sanchez, whilst Japhet Tanganga keeps his place despite the deadline day arrival of Emerson Royal from Barcelona.

They'll be next to Eric Dier and Sergio Reguilon at the back, with Hugo Lloris between the sticks.

Nuno could be boosted by the fitness of Oliver Skipp, who also went off injured during the break but could be available today. If he is, the 20-year-old is likely to maintain his spot alongside Pierre-Emile Hojbjerg and Dele Alli, just as the trio have done in all three league games so far.

Bryan Gil may be in line for his first Premier League start, with Son potentially out injured, whilst Lucas Moura is expected to start if the Dutchman is also out, in what would be the third and final change from their win over Watford two weeks ago.

Finally, Harry Kane should be up front for just the second time this season.

AND in other news, "I'd be stunned": Alasdair Gold drops fresh claim on Harry Kane's future...