Tottenham Hotspur will have to overcome an almighty task later this evening if they are to have any chance of qualifying for Europe's elite stage.

Jose Mourinho's men have sunk seven points adrift of the top four in the Premier League and are out of all domestic cup competitions with everything hinging on tonight's second leg at RB Leipzig.

The Bundesliga outfit carry an away-goal advantage into the tie, so Spurs have it all to do if they are to progress into the next round of the competition.

They are also in a rut of five matches without a victory and also have copious injury troubles mounting up, but what sort of side will Mourinho select? Here's what we are predicting...

There could be as many as five changes from the side that drew 1-1 at Burnley on Saturday evening.

Hugo Lloris is likely to continue as the shot-stopper between the sticks, but there may be changes in front of him with Mourinho sticking with a three-at-the-back system.

Jan Vertonghen shifts inside with Toby Alderweireld making way while Ryan Sessegnon is handed a rare chance at left wing-back. The 19-year-old has only been able to feature 11 times since his summer move from Fulham.

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Meanwhile, in midfield, Harry Winks and Giovani Lo Celso return from having a rest at Turf Moor, which means Oliver Skipp and Tanguy Ndombele, who was pulled off at half-time anyway, drop to the bench,

Dele Alli, Spurs' scorer from the spot against Burnley, will continue to lead the line with Troy Parrott settling for a substitute's role.

He'll again have Erik Lamela next to him on one wing while Lucas Moura takes the reins on the other side following his omission from the starting XI at the weekend.

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There will be no Steven Bergwijn after as the Portuguese boss expects the winger to miss the remainder of the season through injury.

And in other news, Spurs fans in MELTDOWN over latest injury news...